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Original Article
Effect of early postnatal neutropenia in very low birth weight infants born to mothers with pregnancy-induced hypertension
Yang Hee Park, Gyung Min Lee, Jung Min Yoon, Enn Jung Cheon, Kyung Ok Ko, Yung Hyuk Lee, Jae Woo Lim
Clin Exp Pediatr. 2012;55(12):462-469.   Published online December 20, 2012
Purpose

In this study, we aimed to investigate the perinatal clinical conditions of very low birth weight (VLBW) infants born to mothers with pregnancy-induced hypertension (PIH) focusing on the effects of early postnatal neutropenia.

Methods

We reviewed the medical records of 191 VLBW infants who were born at Konyang University Hospital, between March 2003 and May 2011. We retrospectively analyzed the clinical characteristics...

Birth statistics of high birth weight infants (macrosomia) in Korea
Byung-Ho Kang, Joo-Young Moon, Sung-Hoon Chung, Yong-Sung Choi, Kyung-Suk Lee, Ji-Young Chang, Chong-Woo Bae
Clin Exp Pediatr. 2012;55(8):280-285.   Published online August 23, 2012
Purpose

The authors analyzed the trend from the birth-related statistics of high birth weight infants (HBWIs) over 50 years in Korea from 1960 to 2010.

Methods

We used 2 data sources, namely, the hospital units (1960's to 1990's) and Statistics Korea (1993 to 2010). The analyses include the incidence of HBWIs, birth weight distribution, sex ratio, and the relationship of HBWI to maternal...

Case Report
Transient carnitine transport defect with cholestatic jaundice: report of one case in a premature baby
Hyun-Seok Cho, Young Kwang Choo, Hong Jin Lee, Hyeon-Soo Lee
Clin Exp Pediatr. 2012;55(2):58-62.   Published online February 14, 2012

Carnitine (β-hydroxy-γ-trimethylaminobutyric acid) is involved in the transport of long-chain fatty acids into the mitochondrial matrix and the removal of potentially toxic acylcarnitine esters. Transient carnitine transport defect is a rare condition in newborns reported in 1/90,000 live births. In this paper, we describe a case of transient carnitine transport defect found in a premature baby who had prolonged cholestatic...

Review Article
Secular trends of body sizes in Korean children and adolescents: from 1965 to 2010
Jin Soo Moon
Clin Exp Pediatr. 2011;54(11):436-442.   Published online November 30, 2011

An anthropometric survey is one of the most important approaches to use when evaluating the health status of children. Secular trends in body sizes, such as height, weight, head circumference, chest circumference, and body mass index showed significant changes over 40 years in Korea. A series of periodic surveys were conducted in 1967, 1975, 1985, 1997, and 2005 by the...

The changing trends in live birth statistics in Korea, 1970 to 2010
Jae Woo Lim
Clin Exp Pediatr. 2011;54(11):429-435.   Published online November 30, 2011

Although Korean population has been growing steadily during the past four decades, the nation is rapidly becoming an aging society because of its declining birth rate combined with an increasing life expectancy. In addition, Korea has one of the lowest fertility rates in the world due to fewer married couples, advanced maternal age, and falling birth rate. The prevalence of...

Original Article
Outcomes of small for gestational age micropremies depending on how young or how small they are
Hee Joon Yu, Eun Sun Kim, Jin Kyu Kim, Hye Soo Yoo, So Yoon Ahn, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2011;54(6):246-252.   Published online June 30, 2011
Purpose

The outcomes of small for gestational age (SGA) infants especially in extremely low birth weight infants (ELBWIs) are controversial. This study evaluated the mortality and morbidity of ELBWIs, focusing on whether or not they were also SGA.

Methods

The medical records of 415 ELBWIs (birth weight <1,000 g), who were inborn and admitted to the Samsung Medical Center neonatal intensive care unit...

A study on the measurement of the nucleated red blood cell (nRBC) count based on birth weight and its correlation with perinatal prognosis in infants with very low birth weights
Tae Hwan Kil, Ji Yeon Han, Jun Bum Kim, Gyeong Ok Ko, Young Hyeok Lee, Kil Young Kim, Jae Woo Lim
Clin Exp Pediatr. 2011;54(2):69-78.   Published online February 28, 2011
Purpose

The aim of this study was conducted to investigate the mean nRBC count in very low births weight infants (VLBWIs) and to determine the usefulness of the nRBC as an independent prognostic factors of perinatal complications in VLBWIs.

Methods

This study was conducted on 112 VLBWIs who were hospitalized in the neonatal intensive care unit (NICU) of the author's hospital within the...

Case Report
Testicular torsion in the inguinal region in an extremely low birth weight infant
Yu Jin Jung, Jae Min Chung
Clin Exp Pediatr. 2010;53(9):852-854.   Published online September 13, 2010

Testicular torsion is rare in newborn infants. However, its frequency has increased, most of which are reported in full-term infants. We diagnosed and treated testicular torsion in an extremely low birth weight infant (ELBWI). A 2×2 cm red mass was palpable in the left groin of a 24-week-old, 745 g, male newborn at 23 days of age. Left testicular torsion...

Original Article
Effect of severe neonatal morbidities on long term outcome in extremely low birthweight infants
Kyo Yeon Koo, Jeong Eun Kim, Soon Min Lee, Ran Namgung, Min Soo Park, Kook In Park, Chul Lee
Clin Exp Pediatr. 2010;53(6):694-700.   Published online June 23, 2010
Purpose

To assess the validity of individual and combined prognostic effects of severe bronchopulmonary dysplasia (BPD), brain injury, retinopathy of prematurity (ROP), and parenteral nutrition associated cholestasis (PNAC).

Methods

We retrospectively analyzed the medical records of 80 extremely low birthweight (ELBW) infants admitted to the neonatal intensive care unit (NICU) of the Severance Children's Hospital, and who survived to a postmenstrual age of...

Effect of SynagisⓇ (palivizumab) prophylaxis on readmission due to respiratory syncytial virus in very low birth weight infants
Soo Kyoung Park, Yu Jin Jung, Hye Soo Yoo, So Yoon Ahn, Hyun Joo Seo, Seo Heui Choi, Myo Jing Kim, Ga Won Jeon, Soo Hyun Koo, Kyung-Hoon Lee, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2010;53(3):358-363.   Published online March 15, 2010
Purpose : The aim of this study was to determine the efficacy of SynagisⓇ (palivizumab) in reducing the respiratory syncytial virus (RSV) readmission rate in very low birth weight infants (VLBWI ) and the subgroup that showed the most effective vaccination. Methods : We enrolled 350 VLBWI who had been discharged alive from the neonatal intensive care unit of Samsung Medical...
Case Report
High-dose caspofungin salvage in a very-low-birth-weight infant with refractory candidemia
Eun Sun Seo, Geun Hwa Park, Sung Mi Kim, Hye An Jung, Byoung Kuk Kim
Clin Exp Pediatr. 2010;53(2):239-243.   Published online February 15, 2010
Candidiasis is one of the most common causes of late-onset infection among very-low-birth-weight infants (VLBW) in most neonatal intensive care units and is associated with significant morbidity and mortality. Standard therapy consists of the administration of amphotericin B, amphotericin B complex, and fluconazole. In many cases, candidiasis is not easily eradicated, despite the administration of these drugs. We report our...
Original Article
Analysis of prognostic factors of laparotomy for necrotizing enterocolitis in extremely low birth weight infants
Jin Kyu Kim, Yi Sun Kim, Hye Soo Yoo, So Yoon Ahn, Hyun ju Seo, Seo Heui Choi, Soo Kyung Park, Yu Jin Jung, Myo Jing Kim, Ga Won Jeon, Soo Hyun Koo, Kyung-Hoon Lee, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2010;53(2):167-172.   Published online February 15, 2010
Purpose : With improved survival of extremely low birth weight infants (ELBWI), there is an increase in the incidence of necrotizing enterocolitis (NEC) requiring laparotomy, and the risk of morbidity and mortality in these ELBWI is increased. Thus, we determined the prognostic factors in ELBWI who underwent laparotomy for NEC. Methods : We retrospectively reviewed the medical records of 35 ELBWI...
Case Report
A case of pulmonary vascular air embolism in a very-low-birth-weight infant with massive hydrops
Myo Jing Kim, Hee Joon Yu, Cha Gon Lee, Soo Kyoung Park, Yun Sil Chang, Won Soon Park
Clin Exp Pediatr. 2009;52(12):1392-1395.   Published online December 15, 2009
Pulmonary vascular air embolism is a rare and, universally, almost a fatal complication of positive pressure ventilation in newborn infants. Here, we report a case of this unusual complication in a very-low-birth-weight infant who showed the clinical and radiological features of this complication along with pulmonary hypoplasia and massive hydrops. The possible pathogenesis has been discussed and a brief review...
Original Article
Magnetic resonance imagining findings of the white matter abnormalities in the brain of very-low-birth-weight infants
Jae Hyuk Choi, Young Pyo Chang
Clin Exp Pediatr. 2009;52(10):1127-1135.   Published online October 15, 2009
Purpose : To observe the abnormal white matter findings on the magnetic resonance imaging (MRI) scans of very-low- birth-weight (VLBW) infant brains at term-equivalent age and to determine the clinical risk factors for the development of periventricular leukomalacia (PVL). Methods : In all, MRI was performed in 98 VLBW infants and the white matter abnormalities were observed. Clinical risk factors...
Comparative study of newborns of Asian immigrant and Korean women
Hee-ok Park, Jae-woo Lim, Hyun-seung Jin, Jae-won Shim, Min-hee Kim, Chun-soo Kim, Eun-ryoung Kim, Seung-youn Kim, Sang-kee Park, Jung-joo Lee
Clin Exp Pediatr. 2009;52(10):1119-1126.   Published online October 15, 2009
Purpose : This study compares the maternal characteristics and birth outcomes of infants of Asian immigrant mothers from developing countries with those of the infants of Korean mothers. Methods : In this multicenter and retrospective study, Asian immigrant women who had delivered between January 2005 and June 2008 were enrolled from9 Medical Centers. In all, 333 births to Asian immigrant...
Case Report
Postnatal cytomegalovirus infection in an extremely premature infant transmitted via breast milk: A case report
Ji Hye Kim, Eun-Jin Chung, Hyun Kyung Park, Soo Ji Moon, Su-Mi Choi, Sung Hee Oh
Clin Exp Pediatr. 2009;52(9):1053-1058.   Published online September 15, 2009
Cytomegalovirus (CMV) is one of the most commonly encountered viral pathogens in newborn infants and is found in 0.3-2.4% of all live births. It has been demonstrated that 40-96% of seropositive mothers shed the virus via their breast milk. Breast milk containing CMV can cause almost one-third of CMV infections occurring in infants. A case of postnatal CMV infection in...
Original Article
Changes in the outcomes of neonatal intensive care unit at a single center over 12 years
Hyun-Hee Lee, Tae-Yeon Kim, Seon-Hee Shin, Tae-Jung Sung
Clin Exp Pediatr. 2009;52(8):881-887.   Published online August 15, 2009

Purpose:The survival rate of very low birth weight infant (VLBWI) had increased as a result of advances in neonatal intensive care. We evaluated the changes in outcomes of VLBWI who admitted to the neonatal care unit of Hallym University Kangnam Sacred Heart Hospital. Methods:Retrospective review of 339 VLBWI who were born from 1st January 1997 to 31th December 2008 were performed. Outcomes including survival...
Clinical course and prognosis of hemodynamically significant congenital heart defects in very low birth weight infants
Hye Soo Yoo, Ji Eun Kim, Soo Kyoung Park, Hyun Ju Seo, Yoo Jin Jeong, Seo Heui Chio, Soo In Jeong, Sung Hoon Kim, Ji Hyuk Yang, June Huh, Yun Sil Chang, Tae Gook Jun, I Seok Kang, Won Soon Park, Pyo Won Park, Heung Jae Lee
Clin Exp Pediatr. 2009;52(4):481-487.   Published online April 15, 2009
Purpose : This study investigated the clinical course and prognostic factor of very low birth weight infants (VLBWI) with hemodynamically significant congenital heart defects (CHDs). Methods : Medical records of 1,098 VLBWI with birth weight <1,500 g who had been admitted to the neonatal intensive care unit of Samsung Medical Center from October 1994 to December 2007 were reviewed retrospectively. The...
Gastrointestinal surgery in very low birth weight infants : Clinical characteristics
Ji Eun Kim, Hye Soo Yoo, Hea Eun Kim, Soo Kyoung Park, Yoo Jin Jeong, Seo Heui Choi,, Hyun Joo Seo, Yun Sil Chang, Jeong Meen Seo, Won Soon Park, Suk Koo Lee
Clin Exp Pediatr. 2009;52(3):295-302.   Published online March 15, 2009
Purpose : To report our experience of gastrointestinal (GI) operations (OP) performed in very low birth weight infants (VLBWI) and to evaluate their clinical characteristics. Methods : Among the 1,117 VLBWI admitted to the SMC neonatal intensive care unit from November 1994 to February 2007, the medical records of 37 infants who underwent GI OP (except inguinal hernia OP) and 1,080...
The association between serum IGF-1 and neonatal growth and disease in a NICU
Jung Ok Kim, Hae Ri Lim, Heng Mi Kim
Clin Exp Pediatr. 2009;52(2):176-180.   Published online February 15, 2009
Purpose : The objective of this study was to establish the serum IGF-1 level in newborn infants, and investigate its association with growth and diseases. Methods : In a retrospective study, serum IGF-1 levels were measured for newborn infants admitted to NICU at Kyungpook University Hospital from March 2007 to July 2007. Birth data, disease history, and hospital course were...
Review Article
Neurodevelopmental outcomes of very low birth weight infants and extremely low birth weight infants in Korea, 1984-2008
In Kyung Sung
Clin Exp Pediatr. 2009;52(1):14-21.   Published online January 15, 2009
Neurodevelopmental outcomes of very low birth weight infants (VLBWI) and extremely low birth weight infants (ELBWI) in Korea on 14 reports from 1984 to 2008 were analyzed. Follow-up rates were varied from 42.9% to 90.2%. Duration of follow-up ranged from 4 months to 5 years. The prevalence of cerebral palsy (CP) of VLBWI was as follows: 4.3-5.3% in 1980s, 7.1-9.1...
Original Article
Prevalence and trends in obesity among Korean children and adolescents in 1997 and 2005
Kyungwon Oh, Myoung Jin Jang, Na Yeoun Lee, Jin Soo Moon, Chong Guk Lee, Myung Hwan Yoo, Young Taek Kim
Clin Exp Pediatr. 2008;51(9):950-955.   Published online September 15, 2008
Purpose : The objective of this study was to provide current estimates of the prevalence and examine trends of overweight and obesity in children and adolescents. Methods : Height and weight measurements from 183,159 (112,974 in 1997, 70,185 in 2005) children and adolescents aged 2 to 18 years were obtained via the 1997 and 2005 National Growth Survey. Obesity among...
Infantile risk factors for obesity in preschool children
Sun Ju Park, Jae Won Moon, Hyun Ji Kim, Min Jung Cho
Clin Exp Pediatr. 2008;51(8):804-811.   Published online August 15, 2008
Purpose : Childhood obesity is a problem that places a child at great risk for becoming an obese adult. To prevent obesity, it is important to focus on early life risk factors that may contribute to childhood obesity. The aim of this study is to find obesity-causing infantile risk factors in preschool children. Methods : A total of 223 children aged...
Growth and clinical efficacy of fortified human milk and premature formula on very low birth weight infants
Heewon Chueh, Myo Jing Kim, Young-A Lee, Jin-A Jung
Clin Exp Pediatr. 2008;51(7):704-712.   Published online July 15, 2008
Purpose : A prospective, controlled trial was conducted to evaluate growth, efficacy, safety and nutritional status for very low birth weight infants fed with human milk fortified with Maeil human milk fortifier (Maeil HMF ; Maeil Dairies Co., Ltd.). Methods : We enrolled 45 premature infants with a birth weight <1,500 g and gestational age <33 weeks, who were born at...
Review Article
Trends in survival rate for very low birth weight infants and extremely low birth weight infants in Korea, 1967-2007
Ki-Soo Kim, Chung-Woo Bae
Clin Exp Pediatr. 2008;51(3):237-242.   Published online March 15, 2008
To investigate the trends in the survival rate (SR) for very low birth weight infants (VLBW) and extremely low birth weight infants (ELBWI) in Korea, a total of 43 articles pertaining to SR were analyzed, covering the years from 1967 to 2007. The changes in SR were compared using 5 year periods. The SR for VLBWI has increased remarkably, from...
Changes in birth rates of low birth weight and premature infants in Korea over the past 7 years
Min Hee Kim
Clin Exp Pediatr. 2008;51(3):233-236.   Published online March 15, 2008
In recent years, Korea has experienced a steadily declining birth rate, which is a serious social problem in the country. Although living conditions have improved, the birth rates for low birth weight infants and preterm babies has increased because more and more women choose to give birth later in life and the social environment has changed. The rise in low...
Original Article
A survey of body shape perception and weight control of adolescent girls in three areas of Korea
Yoon Lee, Hye-Kyoung Shin, Byung-Min Choi, Baik-Lin Eun, Sang-Hee Park, Kee-Hyoung Lee, Chol Shin
Clin Exp Pediatr. 2008;51(2):134-144.   Published online February 15, 2008
Purpose : This study aimed to investigate body shape perception, weight control behaviors and eating habits of adolescent girls in urban, suburban and rural areas of Korea to obtain basis for establishing adequate weight control program for adolescent. Methods : From May 2002 to November 2002, a cross-sectional questionnaire survey and physical examination were conducted to examine body shape perception, weight...
Review Article
2007 Korean National Growth Charts: review of developmental process and an outlook
Jin Soo Moon, Soon Young Lee, Chung Mo Nam, Joong-Myung Choi, Bong-Keun Choe, Jeong-Wan Seo, Kyungwon Oh, Myoung-Jin Jang, Seung-Sik Hwang, Myung Hwan Yoo, Young Taek Kim, Chong Guk Lee
Clin Exp Pediatr. 2008;51(1):1-25.   Published online January 15, 2008
Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers...
Original Article
Effect of women's first childbearing age on the risk of low birth weight
Jung Ju Lee
Clin Exp Pediatr. 2007;50(12):1206-1211.   Published online December 15, 2007
Purpose : The aim of this study was to investigate the risk of low birth weight associated with delayed first childbearing in Korea. Methods : The national birth certificate data of the singletons and first babies in Korea from January 2001 to December 2003 (n=736,167) was used. Outcome measures were rates of low birth weight infant, very low birth weight...
Case Report
A case of pulmonary thromboembolism in a healthy infant
Woo-Yeon Choi, Young-Seok Choi, Soo-Min Oh, Young-Kuk Cho, Jae-Sook Ma
Clin Exp Pediatr. 2007;50(10):1030-1033.   Published online October 15, 2007
A pulmonary thromboembolism (PTE), which is a sudden blockage in a pulmonary artery, usually due to a blood clot, is rare in children. The clinical presentation is often subtle or masked by the underlying clinical condition and the condition must be suspected during clinical testing. Although the choice of treatment depends on the clinical presentation, anticoagulation is the mainstay of...
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